Red. Swollen. Hot. Painful. Signs of inflammation that no
La Grande back pain patient wants to suffer. Paulette Hugulet, DC, LLC
delivers chiropractic services to reduce back pain
by identifying and addressing any associated
inflammation.
INFLAMMATION AND BACK PAIN RELATED
How can you differentiate if there is
inflammation? Like other issues, researchers search
for ways to measure it. To measure inflammation, researchers look for inflammatory biomarkers, biological markers like tumor
necrosis factor alpha (TNF-α), C-reactive protein (CRP), and interleukin-6,
interleukin-1β, that revealed an increase. Researchers
have discovered that chronic inflammation raised
cytokine production and triggered pro-inflammatory
pathways that may bring about non-specific low back pain. (1)
Researchers detected systemic inflammation in chronic LBP and
may affect transition from acute to persistent low back pain. Specifically,
CRP was discovered to be elevated in acute low back pain patients versus control patients. TNF was greater in back pain
patients particularly in patients with depression. (2) Since
researchers have already verified that inflammation
is linked to back pain, Paulette Hugulet, DC, LLC knows that
inflammation must be decreased in order to
help reduce La Grande back pain.
HOW TO STOP INFLAMMATION
Well, first, know what inflammation does. Researchers
used lipopolysaccharide (LPS) to simulate
intervertebral disc degeneration in trials. They set out
to figure out what may help reduce
the produced back pain that comes with it
and/or even avert the degeneration initially
so we humans don’t have to be subjected to
low back pain at all! That is a tall order
though, Paulette Hugulet, DC, LLC knows. But follow
this: researchers utilized LPS to establish the
degeneration that preceded low back pain. They found
that procyanidin B3 (PRO-B3) found in our diets prevented
the production of inflammatory markers - tumor necrosis factor α (TNF-Α),
interleukin-6 (IL-6), prostaglandin E2 (PGE2) and nitric oxide – linked to disc degeneration. It also prevented the loss of the
disc’s gelatin nucleus pulposus cells and structural damage of
its anulus fibrosus (outer rings of disc). What’s all this signify
to researchers looking for a way to prevent degenerative
disc degeneration (DDD)? PRO-B3 may be looked at as a
treatment agent for intervertebral disc degeneration (IVDD). This is a welcome bit
of information for those 80% of us adults who are on track
to experience IVDD, a major cause of low back pain. (3) Another recent
paper described that the p38 MAPK inflammatory pathway may be able to postpone DDD utilizing the tyrosine
kinase inhibitor, Genistein. (4) That’s hopeful
in the treatment of La Grande back pain and inflammation.
Vitamin D FOR INFLAMMATION
Research says that vitamin D deficiency is linked
with low back pain that is stronger in younger women and in those with more
severe deficiency. (5) Vitamin D deficiency is linked to lumbar
disc disease and more severe low back pain in postmenopausal women. (6) Let
us talk about your vitamin D intake at your next
La Grande chiropractic appointment.
CONTACT Paulette Hugulet, DC, LLC
Listen to this PODCAST with Dr. Sarah Murrow on The Back Doctors Podcast with Dr. Michael Johnson. In this episode, Dr. Murrow and her patient present how the Cox® Technic System alleviated back pain due to disc bulges.